Product info:

The protein encoded by this gene has multiple PDZ domains, which are hallmarks of protein-protein interactions. The encoded protein is known to interact with the HTR2C receptor and may cause it to clump at the cell surface. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names:

MPDZ; HYC2; MUPP1

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Cellular localisation:

Apical cell membrane, Cell junction, Cell membrane, Cell projection, Cytoplasmic side, Peripheral membrane protein, dendrite, postsynaptic cell membrane, postsynaptic density, synapse, synaptosome, tight junction

Isotype:

IgG

Immunogen:

Recombinant fusion protein containing a sequence corresponding to amino acids 1100-1380 of human MPDZ (NP_003820.2).

Positive control:

U-251MG, LO2, 293T, Mouse brain

AA Sequence:

SLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQNTAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNGTLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYPKYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKISQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI

Purification:

Affinity purification

Molecular weight:

Calculated MW: 214kDa/217kDa/218kDa/221kDa Observed MW: 321kDa

Form:

Liquid

Applications:

Request info at info@sobekbio.com

Dilution:

WB 1:200 - 1:2000 IHC 1:50 - 1:200

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com