Product info:

Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion (By similarity. Required for the maintenance of synaptic ultrastructure in the adult retina (By similarity. Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina (By similarity. Suppresses tonic photoreceptor activity and baseline 'noise' by suppression of Ca(2+ vesicle tonic release and the facilitation of evoked synchronous and asynchronous Ca(2+ vesicle release (By similarity.

Alternative names:

CPLX3; CPX-III; CPXIII; Nbla11589

Species reactivity:

Mouse, Rat

Host:

Rabbit

Cellular localisation:

Cell junction, Lipid-anchor, Membrane, synapse

Isotype:

IgG

Immunogen:

Recombinant fusion protein containing a sequence corresponding to amino acids 59-158 of human CPLX3 (NP_001025176.1).

Positive control:

Mouse brain, Mouse eye, Rat brain

AA Sequence:

DAQFTQRKAERATLRSHFRDKYRLPKNETDESQIQMAGGDVELPRELAKMIEEDTEEEEEKASVLGQLASLPGLNLGSLKDKAQATLGDLKQSAEKCHVM

Purification:

Affinity purification

Molecular weight:

Calculated MW: 17kDa Observed MW: 18kDa

Form:

Liquid

Applications:

Request info at info@sobekbio.com

Dilution:

WB 1:500 - 1:2000

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com