Product info:

Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+ uptake into Deiters' cells in the cochlea and contribute to K(+ recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(- extrusion in the kidney and contribute to renal acidification (By similarity.

Alternative names:

SLC12A7; KCC4

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Cellular localisation:

Cell membrane, Multi-pass membrane protein

Isotype:

IgG

Immunogen:

Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human SLC12A7 (NP_006589.2).

Positive control:

Mouse kidney, Mouse liver, Rat kidney

AA Sequence:

MPTNFTVVPVEAHADGGGDETAERTEAPGTPEGPEPERPSPGDGNPRENSPFLNNVEVEQESFFEGKNMA

Purification:

Affinity purification

Molecular weight:

Calculated MW: 28kDa/119kDa Observed MW: 119kDa

Form:

Liquid

Applications:

Request info at info@sobekbio.com

Dilution:

WB 1:500 - 1:2000

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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