Product info:

This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene.

Alternative names:

ACAN; AGC1; AGCAN; CSPG1; CSPGCP; MSK16; SEDK; aggrecan

Species reactivity:

Mouse

Host:

Rabbit

Cellular localisation:

Secreted, extracellular matrix, extracellular space

Isotype:

IgG

Immunogen:

A synthetic peptide corresponding to a sequence within amino acids 350-450 of human Aggrecan (NP_037359.3).

Positive control:

Mouse brain

AA Sequence:

TGEDFVDIPENFFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPSPLEPEEPFTFAPEIGATAFAEVENETGEATRPWGFPTPGL

Purification:

Affinity purification

Molecular weight:

Calculated MW: 239kDa/246kDa/250kDa Observed MW: 230kDa

Form:

Liquid

Applications:

Request info at info@sobekbio.com

Dilution:

WB 1:500 - 1:1000

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com