Product info:

Inhibits fibroblast growth factor (FGF-induced retinal lens fiber differentiation, probably by inhibiting FGF-mediated phosphorylation of ERK1/2 (By similarity. Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells (By similarity.

Alternative names:

SPRY1; hSPRY1

Species reactivity:

Mouse

Host:

Rabbit

Cellular localisation:

Cytoplasm, Membrane, Peripheral membrane protein

Isotype:

IgG

Immunogen:

Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human SPRY1 (NP_005832.1).

Positive control:

Mouse heart

AA Sequence:

MDPQNQHGSGSSLVVIQQPSLDSRQRLDYEREIQPTAILSLDQIKAIRGSNEYTEGPSVVKRPAPRTAPRQEKHERTHEIIPINVNNNYEHRHTSHLGHAVLPSNARGPILSRSTSTGSAASSGSNSSASSEQGLLGRSPPTRPVPGHRSERAIRTQPKQLIVDDLKGSL

Purification:

Affinity purification

Molecular weight:

Calculated MW: 35kDa Observed MW: 32kDa

Form:

Liquid

Applications:

Request info at info@sobekbio.com

Dilution:

WB 1:500 - 1:2000

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com