Product info:

Ca(2+ sensor involved in Ca(2+-dependent exocytosis of secretory vesicles through Ca(2+ and phospholipid binding to the C2 domain. Ca(2+ induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis (By similarity. Plays a role in dendrite formation by melanocytes.

Alternative names:

SytIII; SYT3

Species reactivity:

Mouse, Rat

Host:

Rabbit

Cellular localisation:

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Isotype:

IgG

Immunogen:

Recombinant fusion protein containing a sequence corresponding to amino acids 449-590 of human SYT3 (NP_115674.1).

Positive control:

Mouse brain, Mouse liver, Rat brain, Rat liver

AA Sequence:

TVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSKGLSEKENSE

Purification:

Affinity purification

Molecular weight:

Observed MW: 63kDa

Form:

Liquid

Applications:

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Dilution:

WB 1:500 - 1:2000

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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