Product info:

The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.

Alternative names:

GRIN1; GluN1; MRD8; NMD-R1; NMDA1; NMDAR1; NR1; NMDA 1

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Cellular localisation:

Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, postsynaptic density, synapse

Isotype:

IgG

Immunogen:

A synthetic peptide corresponding to a sequence within amino acids 600-700 of human NMDAR1 (NP_015566.1).

Positive control:

C6, SH-SY5Y, U-87MG, Mouse brain, Mouse eye, Rat liver, Rat brain

AA Sequence:

ALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELS

Purification:

Affinity purification

Molecular weight:

Calculated MW: 99-107kDa Observed MW: 120KDa

Form:

Liquid

Applications:

WB (Mus musculus, Rattus norvegicus) IHC (Homo sapiens)

Dilution:

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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