Product info:

The protein encoded by this gene is a transcriptional regulator and tumor suppressor, serving as an activator of genes involved in both innate and acquired immune responses. The encoded protein activates the transcription of genes involved in the body's response to viruses and bacteria, playing a role in cell proliferation, apoptosis, the immune response, and DNA damage response. This protein represses the transcription of several other genes. As a tumor suppressor, it both suppresses tumor cell growth and stimulates an immune response against tumor cells. Defects in this gene have been associated with gastric cancer, myelogenous leukemia, and lung cancer.

Alternative names:

N/A

Species reactivity:

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Host:

Rabbit

Cellular localisation:

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Isotype:

IgG

Immunogen:

None

Positive control:

293T

AA Sequence:

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Purification:

Potein A/G purification

Molecular weight:

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Form:

Liquid

Applications:

IP (Mus musculus, Homo sapiens, Sus scrofa, Rattus norvegicus) WB (Homo sapiens, Rattus norvegicus, Bos taurus) ChIP (Mus musculus, Rattus norvegicus) Co-IP (Homo sapiens, Mus musculus, Cricetulus griseus) IF (Homo sapiens) IHC (Mus musculus) RIP (Mus musculus)

Dilution:

IP 1:50 - 1:200

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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