Product info:

The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names:

AGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA; BTK

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Cellular localisation:

Cell membrane, Cytoplasm, Nucleus, Peripheral membrane protein

Isotype:

IgG

Immunogen:

A synthetic phosphorylated peptide around Y223 of human Btk (NP_000052.1).

Positive control:

Request info at info@sobekbio.com

AA Sequence:

ALYDY

Purification:

Affinity purification

Molecular weight:

Calculated MW: 76kDa/79kDa Observed MW: Refer to Figures

Form:

Liquid

Applications:

WB (Mus musculus, Rattus norvegicus)

Dilution:

WB 1:500 - 1:2000 IF 1:20 - 1:100

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com