Product info:

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

Alternative names:

PDGFRA; CD140A; PDGFR-2; PDGFR2; GAS9; RHEPDGFRA

Species reactivity:

Human

Host:

Rabbit

Cellular localisation:

Cell membrane, Single-pass type I membrane protein

Isotype:

IgG

Immunogen:

A synthetic phosphorylated peptide around Y849 of human PDGFRA (NP_006197.1).

Positive control:

HepG2

AA Sequence:

SNYVS

Purification:

Affinity purification

Molecular weight:

Calculated MW: 24kDa/82kDa/122kDa Observed MW: 190kDa

Form:

Liquid

Applications:

Request info at info@sobekbio.com

Dilution:

WB 1:500 - 1:2000

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

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