Product info:

The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals.

Alternative names:

ERN1; IRE1; IRE1P; IRE1a; hIRE1p

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Cellular localisation:

Endoplasmic reticulum membrane, Single-pass type I membrane protein

Isotype:

IgG

Immunogen:

A phospho specific peptide corresponding to residues surrounding s724 of human IRE1alpha.

Positive control:

NIH/3T3

AA Sequence:

Email info@sobekbio.com for sequence

Purification:

Affinity purification

Molecular weight:

Calculated MW: 6kDa/109kDa Observed MW: 130KDa

Form:

Liquid

Applications:

WB (Homo sapiens, Mus musculus, Rattus norvegicus, Trachemys scripta elegans)

Dilution:

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com