Product info:

This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL). This protein may also be involved in regulating genes that function in metabolic, inflammatory and cardiovascular processes.

Alternative names:

EAR1; hRev; THRA1; THRAL; ear-1; REVERBA; REVERBalpha

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Cellular localisation:

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Isotype:

IgG

Immunogen:

Recombinant protein of human Rev-Erbα/NR1D1.

Positive control:

HepG2, Mouse liver, Rat brain, Rat lung

AA Sequence:

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Purification:

Affinity purification

Molecular weight:

Calculated MW: 66kDa Observed MW: 75kDa

Form:

Liquid

Applications:

IHC (Mus musculus)

Dilution:

WB 1:500 - 1:2000

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

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