Product info:

CD70 is a member of the TNF family whose expression is upregulated on DCs upon maturation. Its only receptor, CD27, is expressed on T cells and NK cells. The CD70/CD27 pathway promotes effector CD8+ T cells responses (by sustaining survival of CTLs) and influences polarization of CD4+ T cells, as it represents an alternative IL-12-independent pathway of Th1 priming and suppresses effector Th17 function.

Alternative names:

N/A

Species reactivity:

Human

Host:

Rabbit

Cellular localisation:

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Isotype:

IgG

Immunogen:

Recombinant protein of human CD70.

Positive control:

Raji, 293T

AA Sequence:

Email info@sobekbio.com for sequence

Purification:

Affinity purification

Molecular weight:

Observed MW: Refer to figures

Form:

Liquid

Applications:

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Dilution:

WB 1:500 - 1:2000 FC 1:100 - 1:800

Storage buffer:

Buffer: PBS with 0.02% thimerosal, pH7.4.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com