Product info:

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

Alternative names:

PDCD1; CD279; PD-1; PD1; SLEB2; hPD-1; hPD-l; hSLE1

Species reactivity:

Human

Host:

Mouse

Cellular localisation:

Membrane, Single-pass type I membrane protein

Isotype:

IgG

Immunogen:

Recombinant protein of human PD-1/CD279.

Positive control:

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AA Sequence:

Email info@sobekbio.com for sequence

Purification:

Affinity purification

Molecular weight:

Calculated MW: 31kDa Observed MW: Refer to figures

Form:

Liquid

Applications:

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Dilution:

WB 1:500 - 1:2000

Storage buffer:

Buffer: PBS with 0.05% sodium azide, 0.2% BSA, 40% glycerol, pH7.4.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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