Bone Morphogenetic Proteins (BMPs) are a class of Transforming Growth Factor Beta (TGF-β; an activator that can be found in many tissues). It was originally named because it can induce atopic bone formation, and then it is directly or indirectly related to cell development such as cell proliferation and differentiation, apoptosis, and cell communication during morphogenesis. It has an important influence on the development of the eye. Due to its important influence on development, if the gene of the bone-forming protein is mutated, it will cause Axenfeld-Rieger syndrome (an eye-related disease), increased intraocular pressure, glaucoma or anterior body deformity.BMP2 acts in the body as a disulfide-linked homodimer. It plays an important role in inducing the formation of cartilage and hard bone and the differentiation of osteoblasts. In addition, it is currently considered to be a regulator of retinoids.