Product overview:

SERPINB6 mouse monoclonal antibody, clone LBI3H3

Field of research:

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Summary:

The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]

Alternative names:

CAP; DFNB91; MSTP057; PI-6; PI6; PTI; SPI3

Species reactivity:

Human, Monkey, Mouse

Host:

Mouse

Target:

SERPINB6

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human SERPINB6(NP_004559) produced in HEK293T cell.

Clone:

LBI3H3

Conjugation:

Unconjugated

Gene name:

serpin family B member 6

Symbol:

SERPINB6

Pathway:

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Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1.08 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000, IF 1:100, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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