Product overview:

CAST (Calpastatin) mouse monoclonal antibody, clone LBI1E7

Field of research:

Request info at info@sobekbio.com

Summary:

The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]

Alternative names:

BS-17; PLACK

Species reactivity:

Human

Host:

Mouse

Target:

CAST

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human CAST(NP_001741) produced in HEK293T cell.

Clone:

LBI1E7

Conjugation:

Unconjugated

Gene name:

calpastatin

Symbol:

CAST

Pathway:

Request info at info@sobekbio.com

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.62 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com