Product overview:

DTNB (Dystrobrevin beta) mouse monoclonal antibody, clone LBI3H8

Field of research:

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Summary:

This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Alternative names:

MGC17163; MGC57126

Species reactivity:

Human, Monkey, Mouse, Rat

Host:

Mouse

Target:

DTNB

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human DTNB(NP_899205) produced in HEK293T cell.

Clone:

LBI3H8

Conjugation:

Unconjugated

Gene name:

dystrobrevin beta

Symbol:

DTNB

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.98 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000, IF 1:100, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

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