Product overview:

ALG2 mouse monoclonal antibody, clone LBI2A3

Field of research:

Metabolic pathways, N-Glycan biosynthesis

Summary:

This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii). Alternative splicing results in multiple transcript variants. [provided by RefSeq]

Alternative names:

CDGIi; hALPG2; NET38

Species reactivity:

Human

Host:

Mouse

Target:

ALG2

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human ALG2(NP_149078) produced in HEK293T cell.

Clone:

LBI2A3

Conjugation:

Unconjugated

Gene name:

ALG2 alpha-1,3/1,6-mannosyltransferase

Symbol:

ALG2

Pathway:

Metabolic pathways, N-Glycan biosynthesis

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.83 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, IHC 1:150, IF 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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