Product overview:

KCNJ3 (GIRK1 ) mouse monoclonal antibody, clone LBI2E4

Field of research:

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Summary:

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex. [provided by RefSeq]

Alternative names:

GIRK1; KGA; KIR3.1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

KCNJ3

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 279-501 of human KCNJ3(NP_002230) produced in E.coli.

Clone:

LBI2E4

Conjugation:

Unconjugated

Gene name:

potassium inwardly rectifying channel subfamily J member 3

Symbol:

KCNJ3

Pathway:

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Function:

Druggable Genome, Ion Channels: Potassium, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.66 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, IF 1:100, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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