Product overview:

KCNAB1 (Kv beta 1) mouse monoclonal antibody, clone LBI6E5

Field of research:

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Summary:

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes three distinct isoforms which are encoded by three alternatively spliced transcript variants of this gene. These three isoforms are beta subunits, which form heteromultimeric complex with alpha subunits and modulate the activity of the pore-forming alpha subunits. [provided by RefSeq]

Alternative names:

AKR6A3; hKvb3; hKvBeta3; KCNA1B; KV-BETA-1; Kvb1.3

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

KCNAB1

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human KCNAB1(NP_751891) produced in HEK293T cell.

Clone:

LBI6E5

Conjugation:

Unconjugated

Gene name:

potassium voltage-gated channel subfamily A regulatory beta subunit 1

Symbol:

KCNAB1

Pathway:

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Function:

Druggable Genome, Ion Channels: Other

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.53 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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