Product overview:

CDH2 (N Cadherin) mouse monoclonal antibody, clone LBI2G7

Field of research:

Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cell adhesion molecules (CAMs)

Summary:

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product. [provided by RefSeq]

Alternative names:

CD325; CDHN; CDw325; NCAD

Species reactivity:

Human, Monkey, Mouse, Rat, Dog

Host:

Mouse

Target:

CDH2

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human CDH2(NP_001783) produced in HEK293T cell.

Clone:

LBI2G7

Conjugation:

Unconjugated

Gene name:

cadherin 2

Symbol:

CDH2

Pathway:

Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cell adhesion molecules (CAMs)

Function:

Druggable Genome, ES Cell Differentiation/IPS, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.77 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000, IHC 1:150, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com