Product overview:

LPAR1 (EDG2) mouse monoclonal antibody, clone LBI1G6

Field of research:

Gap junction, Neuroactive ligand-receptor interaction

Summary:

The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene [provided by RefSeq, Jul

Alternative names:

edg-2; EDG2; Gpcr26; GPR26; LPA-1; LPA1; Mrec1.3; OTTHUMP00000021904; rec.1.3; vzg-1; VZG1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

LPAR1

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human LPAR1(NP_001392) produced in HEK293T cell.

Clone:

LBI1G6

Conjugation:

Unconjugated

Gene name:

lysophosphatidic acid receptor 1

Symbol:

LPAR1

Pathway:

Gap junction, Neuroactive ligand-receptor interaction

Function:

Druggable Genome, GPCR, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.8 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IF 1:100, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com