Product overview:

RBBP7 (RbAp46) mouse monoclonal antibody, clone LBI5A4

Field of research:

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Summary:

This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Alternative names:

RbAp46

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

RBBP7

Isotype:

IgG1

Immunogen:

Full length human recombinnat protein of RBBP7(NP_002884) produced in HEK293T cell.

Clone:

LBI5A4

Conjugation:

Unconjugated

Gene name:

RB binding protein 7, chromatin remodeling factor

Symbol:

RBBP7

Pathway:

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Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.84 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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