Product overview:

UNG mouse monoclonal antibody, clone LBI2B5

Field of research:

Base excision repair, Primary immunodeficiency

Summary:

This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq]

Alternative names:

DGU; HIGM4; HIGM5; UDG; UNG1; UNG2; UNG15

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

UNG

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human UNG(NP_550433) produced in HEK293T cell.

Clone:

LBI2B5

Conjugation:

Unconjugated

Gene name:

uracil DNA glycosylase

Symbol:

UNG

Pathway:

Base excision repair, Primary immunodeficiency

Function:

Druggable Genome, Stem cell - Pluripotency

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.82 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150, IF 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com