Product overview:

CDKN3 mouse monoclonal antibody, clone LBI2E11

Field of research:

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Summary:

The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

Alternative names:

CDI1; CIP2; KAP; KAP1

Species reactivity:

Human, Mouse

Host:

Mouse

Target:

CDKN3

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human CDKN3(NP_005183) produced in HEK293T cell.

Clone:

LBI2E11

Conjugation:

Unconjugated

Gene name:

cyclin dependent kinase inhibitor 3

Symbol:

CDKN3

Pathway:

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Function:

Druggable Genome, Phosphatase

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.56 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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