Product overview:

EIF2B3 mouse monoclonal antibody, clone LBI1H3

Field of research:

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Summary:

The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Alternative names:

EIF-2B; EIF2Bgamma

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

EIF2B3

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human EIF2B3(NP_065098) produced in HEK293T cell.

Clone:

LBI1H3

Conjugation:

Unconjugated

Gene name:

eukaryotic translation initiation factor 2B subunit gamma

Symbol:

EIF2B3

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.66 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150, IF 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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