Product overview:

PSMB4 (Proteasome subunit beta type 4 ) mouse monoclonal antibody, clone LBI2C9

Field of research:

Proteasome

Summary:

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. [provided by RefSeq]

Alternative names:

HN3; HsN3; PROS-26; PROS26

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

PSMB4

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human PSMB4(NP_002787) produced in HEK293T cell.

Clone:

LBI2C9

Conjugation:

Unconjugated

Gene name:

proteasome 20S subunit beta 4

Symbol:

PSMB4

Pathway:

Proteasome

Function:

Druggable Genome, Protease

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.59 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com