Product overview:

PNPO mouse monoclonal antibody, clone LBI1G9

Field of research:

Metabolic pathways, Vitamin B6 metabolism

Summary:

The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.

Alternative names:

HEL-S-302; PDXPO

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

PNPO

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human PNPO(NP_060599) produced in HEK293T cell.

Clone:

LBI1G9

Conjugation:

Unconjugated

Gene name:

pyridoxamine 5'-phosphate oxidase

Symbol:

PNPO

Pathway:

Metabolic pathways, Vitamin B6 metabolism

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:4000, IHC 1:150, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com