Product overview:

DOK2 mouse monoclonal antibody, clone LBI2D10

Field of research:

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Summary:

The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq]

Alternative names:

p56DOK; p56dok-2

Species reactivity:

Human, Monkey, Mouse, Rat, Dog

Host:

Mouse

Target:

DOK2

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human DOK2(NP_003965) produced in HEK293T cell.

Clone:

LBI2D10

Conjugation:

Unconjugated

Gene name:

docking protein 2

Symbol:

DOK2

Pathway:

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Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.43 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:200~500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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