Product overview:

XPNPEP3 mouse monoclonal antibody, clone LBI4B8

Field of research:

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Summary:

The protein encoded by this gene belongs to the family of X-pro-aminopeptidases that utilize a metal cofactor, and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position. This protein has been shown to localize to the mitochondria of renal cells, and have a role in ciliary function. Mutations in this gene are associated with nephronophthisis-like nephropathy-1. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene, however, expression of some of these isoforms in vivo is not known.

Alternative names:

APP3; ICP55; NPHPL1

Species reactivity:

Human, Monkey, Mouse, Rat, Dog

Host:

Mouse

Target:

XPNPEP3

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human XPNPEP3(NP_071381) produced in HEK293 cell.

Clone:

LBI4B8

Conjugation:

Unconjugated

Gene name:

X-prolyl aminopeptidase 3

Symbol:

XPNPEP3

Pathway:

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Function:

Druggable Genome, Protease

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.86 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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