Product overview:

PDE1B mouse monoclonal antibody, clone LBI1D6

Field of research:

Calcium signaling pathway, Progesterone-mediated oocyte maturation, Purine metabolism

Summary:

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011]

Alternative names:

PDE1B1; PDES1B

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

PDE1B

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human PDE1B(NP_000915) produced in HEK293T cell.

Clone:

LBI1D6

Conjugation:

Unconjugated

Gene name:

phosphodiesterase 1B

Symbol:

PDE1B

Pathway:

Calcium signaling pathway, Progesterone-mediated oocyte maturation, Purine metabolism

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.74 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IF 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com