Product overview:

PPM1B mouse monoclonal antibody, clone LBI3G9

Field of research:

MAPK signaling pathway

Summary:

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq]

Alternative names:

PP2C-beta; PP2C-beta-X; PP2CB; PP2CBETA; PPC2BETAX

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

PPM1B

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human PPM1B(NP_002697) produced in HEK293 cell.

Clone:

LBI3G9

Conjugation:

Unconjugated

Gene name:

protein phosphatase, Mg2+/Mn2+ dependent 1B

Symbol:

PPM1B

Pathway:

MAPK signaling pathway

Function:

Druggable Genome, Phosphatase, Stem cell - Pluripotency

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.97 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com