Product overview:

GATM mouse monoclonal antibody, clone LBI1E3

Field of research:

Arginine and proline metabolism, Glycine, serine and threonine metabolism, Metabolic pathways

Summary:

This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders. [provided by RefSeq]

Alternative names:

AGAT; AT; CCDS3

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

GATM

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human GATM(NP_001473) produced in HEK293T cell.

Clone:

LBI1E3

Conjugation:

Unconjugated

Gene name:

glycine amidinotransferase

Symbol:

GATM

Pathway:

Arginine and proline metabolism, Glycine, serine and threonine metabolism, Metabolic pathways

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.95 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com