Product overview:

PA2G4 (EBP1) mouse monoclonal antibody, clone LBI1D3

Field of research:

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Summary:

This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified. [provided by RefSeq]

Alternative names:

EBP1; HG4-1; p38-2G4

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

PA2G4

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human PA2G4 (NP_006182) produced in HEK293T cell.

Clone:

LBI1D3

Conjugation:

Unconjugated

Gene name:

proliferation-associated 2G4

Symbol:

PA2G4

Pathway:

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Function:

Druggable Genome, Protease, Stem cell - Pluripotency

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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