Product overview:

IRF6 mouse monoclonal antibody, clone LBI2C10

Field of research:

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Summary:

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.

Alternative names:

LPS; OFC6; PIT; PPS; PPS1; VWS; VWS1

Species reactivity:

Human, Mouse, Rat, Dog

Host:

Mouse

Target:

IRF6

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human IRF6(NP_006138) produced in HEK293T cell.

Clone:

LBI2C10

Conjugation:

Unconjugated

Gene name:

interferon regulatory factor 6

Symbol:

IRF6

Pathway:

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Function:

ES Cell Differentiation/IPS, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.54 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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