Product overview:

RGS5 mouse monoclonal antibody, clone LBI1E3

Field of research:

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Summary:

This gene encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. This gene is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. This gene is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names:

MST092; MST106; MST129; MSTP032; MSTP092; MSTP106; MSTP129

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

RGS5

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-181 of human RGS5 (NP_003608) produced in E.coli.

Clone:

LBI1E3

Conjugation:

Unconjugated

Gene name:

regulator of G protein signaling 5

Symbol:

RGS5

Pathway:

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Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.58 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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