Product overview:

SH2B3 (LNK) mouse monoclonal antibody, clone LBI1F6

Field of research:

Neurotrophin signaling pathway

Summary:

This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus.

Alternative names:

IDDM20; LNK

Species reactivity:

Human

Host:

Mouse

Target:

SH2B3

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human SH2B3 (NP_005466) produced in HEK293T cell.

Clone:

LBI1F6

Conjugation:

Unconjugated

Gene name:

SH2B adaptor protein 3

Symbol:

SH2B3

Pathway:

Neurotrophin signaling pathway

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.43 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, IF 1:100, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com