Product overview:

COASY mouse monoclonal antibody, clone LBI3D5

Field of research:

Metabolic pathways, Pantothenate and CoA biosynthesis

Summary:

Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. COASY is a bifunctional enzyme that catalyzes the 2 last steps in CoA synthesis. These activities are performed by 2 separate enzymes, phosphopantetheine adenylyltransferase (PPAT; EC 2.7.7.3) and dephospho-CoA kinase (DPCK; EC 2.7.1.24), in prokaryotes (Daugherty et al., 2002 [PubMed 11923312]). [supplied by OMIM]

Alternative names:

DPCK; NBIA6; NBP; pOV-2; PPAT; UKR1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

COASY

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human COASY (NP_079509) produced in HEK293T cell.

Clone:

LBI3D5

Conjugation:

Unconjugated

Gene name:

Coenzyme A synthase

Symbol:

COASY

Pathway:

Metabolic pathways, Pantothenate and CoA biosynthesis

Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.58 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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