Product overview:

STAT4 mouse monoclonal antibody, clone LBI 4H4

Field of research:

Jak-STAT signaling pathway

Summary:

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug

Alternative names:

SLEB11

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

STAT4

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human STAT4 (NP_003142) produced in HEK293T cell.

Clone:

LBI 4H4

Conjugation:

Unconjugated

Gene name:

signal transducer and activator of transcription 4

Symbol:

STAT4

Pathway:

Jak-STAT signaling pathway

Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.35 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com