Product overview:

ETF1 (eRF1) mouse monoclonal antibody, clone LBI2E3

Field of research:

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Summary:

This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in coding and non-coding transcript variants. Pseudogenes of this gene are found on chromosomes 5, 7 and X. [provided by RefSeq, Jan 2012]

Alternative names:

D5S1995; ERF; ERF1; RF1; SUP45L1; TB3-1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

ETF1

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human ETF1 (NP_004721) produced in HEK293T cell.

Clone:

LBI2E3

Conjugation:

Unconjugated

Gene name:

eukaryotic translation termination factor 1

Symbol:

ETF1

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.97 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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