Product overview:

NFKBIZ mouse monoclonal antibody, clone LBI1E8

Field of research:

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Summary:

This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Alternative names:

IKBZ; INAP; MAIL

Species reactivity:

Human, Rat

Host:

Mouse

Target:

NFKBIZ

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human NFKBIZ (NP_113607) produced in E.coli.

Clone:

LBI1E8

Conjugation:

Unconjugated

Gene name:

NFKB inhibitor zeta

Symbol:

NFKBIZ

Pathway:

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Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.58 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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