Product overview:

PRKAR1B (PKA regulatory subunit I beta) mouse monoclonal antibody, clone LBI2A3

Field of research:

Apoptosis, Insulin signaling pathway

Summary:

Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP. [supplied by OMIM, Jun 2009]

Alternative names:

PRKAR1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

PRKAR1B

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human PRKAR1B (NP_002726) produced in HEK293T cell.

Clone:

LBI2A3

Conjugation:

Unconjugated

Gene name:

protein kinase cAMP-dependent type I regulatory subunit beta

Symbol:

PRKAR1B

Pathway:

Apoptosis, Insulin signaling pathway

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.57 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com