Product overview:

DCK mouse monoclonal antibody, clone LBI3F5

Field of research:

Purine metabolism, Pyrimidine metabolism

Summary:

Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq, Jul 2008]

Alternative names:

MGC117410; MGC138632

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

DCK

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human DCK (NP_000779) produced in HEK293T cell.

Clone:

LBI3F5

Conjugation:

Unconjugated

Gene name:

deoxycytidine kinase

Symbol:

DCK

Pathway:

Purine metabolism, Pyrimidine metabolism

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com