Product overview:

HAND1 mouse monoclonal antibody, clone LBI1G10

Field of research:

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Summary:

The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation. [provided by RefSeq]

Alternative names:

bHLHa27; eHand; Hxt; Thing1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

HAND1

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human HAND1 (NP_004812) produced in E.coli.

Clone:

LBI1G10

Conjugation:

Unconjugated

Gene name:

heart and neural crest derivatives expressed 1

Symbol:

HAND1

Pathway:

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Function:

Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.82 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, IF 1:100, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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