Product overview:

VASP mouse monoclonal antibody, clone LBI4D6

Field of research:

Fc gamma R-mediated phagocytosis, Focal adhesion, Leukocyte transendothelial migration

Summary:

Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq]

Alternative names:

vasodilator-stimulated phosphoprotein

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

VASP

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human VASP(NP_003361) produced in 293T Cell.

Clone:

LBI4D6

Conjugation:

Unconjugated

Gene name:

vasodilator stimulated phosphoprotein

Symbol:

VASP

Pathway:

Fc gamma R-mediated phagocytosis, Focal adhesion, Leukocyte transendothelial migration

Function:

Druggable Genome, Stem cell - Pluripotency

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com