Product overview:

UBA2 mouse monoclonal antibody, clone LBI4A3

Field of research:

Ubiquitin mediated proteolysis

Summary:

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]). [supplied by OMIM]

Alternative names:

ARX; HRIHFB2115; SAE2

Species reactivity:

Human, Monkey, Mouse, Rat, Dog

Host:

Mouse

Target:

UBA2

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human UBA2 (NP_005490) produced in HEK293T cell.

Clone:

LBI4A3

Conjugation:

Unconjugated

Gene name:

ubiquitin like modifier activating enzyme 2

Symbol:

UBA2

Pathway:

Ubiquitin mediated proteolysis

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000, IHC 1:150, IF 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com