Product overview:

DTNA (Dystrobrevin alpha) mouse monoclonal antibody, clone LBI2F9

Field of research:

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Summary:

The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq]

Alternative names:

D18S892E; DRP3; DTN; DTN-A; LVNC1

Species reactivity:

Human, Monkey, Mouse, Rat

Host:

Mouse

Target:

DTNA

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human DTNA (NP_116761) produced in HEK293T cell.

Clone:

LBI2F9

Conjugation:

Unconjugated

Gene name:

dystrobrevin alpha

Symbol:

DTNA

Pathway:

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Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.72 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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