Product overview:

GPHN (Gephyrin) mouse monoclonal antibody, clone LBI3C6

Field of research:

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Summary:

This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known. [provided by RefSeq]

Alternative names:

GEPH; GPH; GPHRYN; HKPX1; MOCODC

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

GPHN

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human GPHN (NP_065857) produced in HEK293T cell.

Clone:

LBI3C6

Conjugation:

Unconjugated

Gene name:

gephyrin

Symbol:

GPHN

Pathway:

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Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.83 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:1000~2000, IHC 1:150, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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