Product overview:

NMNAT1 mouse monoclonal antibody, clone LBI1G4

Field of research:

Metabolic pathways, Nicotinate and nicotinamide metabolism

Summary:

The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca(2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD (Zhang et al., 2003 [PubMed 12574164]). [supplied by OMIM]

Alternative names:

LCA9; NMNAT; PNAT1; SHILCA

Species reactivity:

Human

Host:

Mouse

Target:

NMNAT1

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human NMNAT1 (NP_073624) produced in HEK293T cell.

Clone:

LBI1G4

Conjugation:

Unconjugated

Gene name:

nicotinamide nucleotide adenylyltransferase 1

Symbol:

NMNAT1

Pathway:

Metabolic pathways, Nicotinate and nicotinamide metabolism

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.67 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000, IHC 1:150, FLOW 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com